I was told don't fit a TRV to room with wall thermostat. However I could not get the room, in my case to hall, to do as wanted, there was a large radiator in the hall, with coats hung over it, and a outside door, so hall radiator set to warm up reasonable fast to reheat hall when door is opened and to dry coats, to get other rooms warm needed to set hall thermostat to around 25°C which would result in house getting too hot as summer arrived.
So I broke the rules, I fitted a TRV and a wall thermostat in the same room, the hall, I set wall thermostat to 19°C which I felt was a good summer cut off point, the TRV set to defrost, then bit by bit I turned the TRV up, took a few days, until I noted the wall thermostat turn off. At which point I left them both alone. It works, when the front door is opened it cools the TRV and wall thermostat and heating switches on, when it hits around 17.5°C then the TRV starts to restrict the water flow and the radiator starts to cool, but it will in fullness of time get hall to 19.5°C which will turn wall thermostat off.
This controls my boiler, rooms are controlled by the TRV's in each room. However at 3 am hall still at 19°C and really over night I want whole house to cool, so have a programmer which switches off central heating at around 10:30 pm and on again at 6:00 am, this can mean over night it could get very cold, so a second programmable thermostat in kitchen takes over at night, set to around 17°C allows house to cool over night, but only until the kitchen hits 17°C then boiler cuts in again.
It is not a perfect system, but programmable thermostat was in stock so cost me nothing, so whole control system was cheap, OK the eTRV in mothers bedroom and living room were a little expensive £72.99 but really the heads at £22.51 would have done the job, as I don't need to alter with my phone, but bedrooms upstairs have little more than back ground heat, standard TRV work well enough, so no point altering temperature according to time of day.
The two down stairs rooms do have varying temperatures through the day, however my thoughts of switching off and on or rather up and down as no option for off 16°C is minimum setting, simply did not work, the rooms simply took too long to cool, heating was faster, but typical set to 16°C at 9 pm and back to 20°C at 6 am the rooms never got to 16°C on a really cold night might hit 17°C heat up was a lost faster, by 8 am back to 20°C. However still two hours, and idea was to use phone so when within 10 miles from home heating would auto switch on, but for 2 hours needed around 150 miles from home, and putting it simply we rarely ever travelled that far from home.
Yes we can go into the app on the phone and change temperature, but whole idea is to be automatic, rather defeats the object if you have to access the app. So it ended up working solely on time, and these
are half the price and would do what I now do with my wifi versions. I got the Energenie MiHome as also wanted sockets with remote and fixed times etc and same hub did both.
I expect once traced you will find you have two zones, but likely it will not work as you expect with Nest as controlling just two rooms is not really going to work too well, likely you will want to control all rooms, to drop or raise the hall in my house by 2°C does not cause the other rooms to vary, OK completely off yes, but any small change is compensated by the TRV so hall may get cooler or warmer, but other rooms stay the same.