In theory the more chambers a frame has the more thermally effective it is, I guess this would also increase the sound proofing.
Most standard PVC profiles have 4-7 chambers, Unless you went with something like a Residence 9 windows that is 100mm thick and has 9 chambers (its also 3-4 times the price of normal windows).
Here is something I got from one of the glass manufacturers that I used to give to my customers to help them decide on ratings:
A,B or C rated windows?
What is the average saving to householder between A, B & C rated windows in terms of energy and cost savings?
A, B and C rated windows are all much more energy efficient than standard windows. That said, there are differences in performance of energy efficient windows with A B and C ratings;
• Changing existing single-glazed, timber windows to Band C windows in a semi detached, gas fuelled house would be expected to save £4350 in heating costs and 11 tonnes CO2 over 20 years.
• If the new windows are instead B-rated then the savings increase to £4650 and 11.5 tonnes CO2 .
• And, if the new windows are instead A-rated then the savings increase to nearly £5000 and over 12 tonnes CO2 .
The above shows that achievement of the level C displays significant savings over existing windows with higher ratings of B and A delivering further smaller incremental savings above C.
The only physical difference between our A & B rated windows is coating on the glass and the gas inside the unit.
Using the above example fitting A rated rather than B rated would save about £350 on heating bills over 20 years which is a £17.50 saving per year.