Ok what i suggest is you check Windows hasn't got your device drive letter confused and is finding it conflicts with a device already plugged in.
CLick on the start button
Select 'run'
type 'Compmgmt.msc'
hit enter
You should see a computer management snapin pop up
Look down the lefthand side for 'Disk Management'
Each disc should have a brief description and a drive letter C: D: etc.
If you see one without a letter right click and select "change drive letter and paths' (Or check to see if there's a warning about the partition on that disc. )
Add a letter and click ok.
Goto explorer and look for drive letter you just assigned.
Otherwise disc could be s*****d and i hope you dont have any important data on there. (see get a Nas thread!)