I do see the problem.
With Hive or any other Smart thermostat zones are made with the TRV heads rather than with zone valves.
If using a non modulating boiler however then you can use a standard S plan, the two Hive thermostats can work the two zone valves which in turn run the boiler.
Using a modulating boiler you remove or combine the motorised valves as not really required, well not required with non modulating really, the TRV heads are programmed to produce not just two zones but a zone for every room.
However the down side is the cost of Hive TRV heads, at £80 a pop, it gets rather expensive, and since Hive is not Opentherm where Tado and EvoHome is, Hive may not be best selection.
Worcester Bosch is also a problem. It does not support OpenTherm. As far as I am aware Worcester Bosch uses Wave, this is also a problem as it only works in one room, rather a silly selection in anything but a open plan house.
However you can only **** with the **** you have, so in some way you need to botch it up to work.
So question is why Hive? The normal reason for a thermostat with a modulating boiler is to turn off the boiler to stop it cycling, but Hive is normally used to allow remote control, so if that is the case, how with zone valves you are going to use one Hive thermostat I don't know?
I would say it is a case of pricing up the alternatives, so if looking at 2 up and 2 down £100 for Hive fitting a second hive will cost £100 and fitting Hive TRV heads will cost £320 and as you increase rooms so the price goes up, but Hive wall thermostat and Hive TRV heads is how it should be done, so what are you intending?
Lucky I selected Nest, the wall thermostat is more expensive, but the TRV heads (Energenie) are cheaper.
The other option is to cheat, you can get TRV electronic heads for £10, with Bluetooth still only £15 each, and if programmed the same as the wall thermostat then it would work, but then can't use the remote feature of Hive.
The wiring diagram easy
but how your going to use it is another question.