It does seem odd when you first look at order, but it allows backwards compatibility, so centre two are a pair, then next pair either side of centre two so still central, then when extra 2 pairs added they are to left and right or original 2 pairs. As said every pair is twisted to ensure the impedance is correct, the technology is called transmission lines, even main power in Africa where the lines run 1000's of Km you can have problems, but in the main lower frequency signals do not have a problem, as you reach HF you see 300Ω ribbon cable, the into coax where you have 95Ω, 75Ω, and 50Ω with computer were 95Ω and TV 75Ω and CB and Amateur radio 50Ω. Cross over networks can be built to change the impedance, in radio called balums.
The power is reflected back if the impedance is wrong, CB uses called is swr it is the ratio of power out to reflected power called "Voltage standing wave ratio" and the longer the cable the greater the losses so a patch lead if 1 goes to 1 etc then it will work OK, but with a long run it will fail.