What I meant was:-
When the system is on, the pump is running. If the thermostatic valves close down (because every room is up to temperature), then as they close down they can start to make a wooshing sound as the pressure builds up. it's a bit like putting your thumb over the end of the garden hose, it's easy to slow the flow a bit, but surprisingly hard to shut it right off. As you close it off, the pressure rises. High pressure equals noise.
You can establish if this is your problem by going to the radiator and opening the valve a bit (or closing it as no flow equals no noise). if the noise changes/ goes away, then that proves the case.
The remedy is to fit a bypass circuit (this is already built in to some boilers, particularly combis), which automatically opens when the condition occurs and allows the water an escape route round the system, but not through the radiators. If you have a bypass, it may need to be adjusted to get everything working properly. There are other ways to deal with this, such as variable speed pumps, but they aren't relevant to a combi installation, because it has it's own built in pump.
So Macbee needs to trying lowering the setting on the bypass valve as does LesP. If the setting is too low, the hot water may go round the bypass circuit only and rarely if ever get to the rads, so it's a bit of trial and error. Or look at the Danfoss site for their advice on setting their bypass valve. My bypass valve at home works fine set at the minimum possible pressure, but I have a variable speed pump. All I hear is the boiler, and that is very quiet.