Bringing up an old thread here which is relevant as I used the content to fit a system in an average semi.
I took note of the Intergas boiler and the low loss header to give zoning of upstairs and down and independent TRV temperature control in each room with no central thermostat control.
A low loss header was made up using 28mm pipe and fittings like this, but running horizontally under the boiler.
The two heating zones could have different flows through their own circuits, and sometimes very low flows, so the low loss header guarantees a constant high flow through the boiler giving full boiler protection. The flow and returns to each heating zone were 22mm. The two heating flows were taken from one end of the header. The header also had the filling loop attached. I thought the header of 28mm may be too small, and I was prepared to up the size after testing, which would not be a great job to do, but it works fine.
A 40 kilowatt Intergas combi was used.