All expansion vessels should be sited with there tapping at the top. However many combi have them the wrong way up. But hey the only way most manufacturers make any money is with spares. Another reason you should never fit combis.
Sounds like a load of rubbish to me. Before the water is admitted into the pipework the bladder completely fills the vessel. So there could only be a bit of trapped air in the connecting pipework. If any air is trapped then it won't take long for it to be absorbed into the water under 3 bar pressure. So after a few days it will all have gone.