Let's just say is can be "interesting", but perfectly doable with the modern generation of lightweight cordless saws - not so sure I'd try it with a corded saw though. The biggest problem is dealing with all the crud you get pelted in the face with - makes hard hat, goggles and FFP3 mask a necessity. A sharpish blade will just slice through even hardened drywall screws with just a bit of sparking, but the PB does blunt blades quite quickly.
A mulitool makes for a far less "buttock clenching" experience - but the blades don't last long, so cheapies are the best to use IMHO
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