Had exactly the same problem on Friday. Checked all the parameters, followed the fault diagnosis, confirmed with Potterton. PCB was dead on A2 terminals 5 and 7. Got a surge upto 50v then died. Installed new pcb following correct procedure (some new wiring for earths and pcb layout changed, new part no. for pcb 5112380), immediately indicated another fault - 30 and 40 deg C signs for flame and safety stat showing at same time. Checked stat, then checked for 230v across A1 3 and 5, continuity and resistance check on overheat stat, good. Spoke to Potterton, they asked me to recheck all over the phone, conclusion faulty pcb. So having experienced this a few times before, and not just on Potterton's, I can confirm that it is possible that a new pcb can be faulty.
It is unlikely the burner pressure, combustion, and FSD change when putting in a new pcb but I agree that if the boiler works after installing the pcb these parameters should be checked as a standard to ensure correct performance. That is what are trained to do as a routine.