When I lived in York, I used to work for a research agency down in Leatherhead. I was officially based at home, but had to go down once or twice a week.
Funnily enough, at the time, I thought nothing of getting up at 3.45, leaving home at 4, trudging 230 miles down the A64, A1, M18, M1, A43, M40 & M25, but nowadays, if I ever have to get out of bed before 7 I feel like I've been shot in the head.