On the 35KW boiler and large house. My house isn't small but given the variance in sizing, I am inclined to over size rather than under. Worecester also advised me that the 35 CDI boiler is fully modulated which means it can be throttled back.
I would welcome your thoughts on the above.
A boiler should be sized on the heat losses of the building at the lowest likely outside temperature. The same information is used to size the radiators.
Modulating burners are there so that when the exterior temperature is not at the lowest expected and the heat losses of the building are less, the heat input to the system is also reduced.
They are not there so that people can bung in any boiler they happen to find and hope the boiler output can be adjusted to something appropriate.
As with the electrical side, there is a lot more to heating systems than randomly selecting items from a catalogue and hoping they will work as intended.
You should find someone who can design the complete system.