You are seriously loosing a lot of heat somewhere. Is it double glazed, are the outer doors modern sealing ones, has it cavity wall insulation, is it a dormer style???
For comparison - I have all of the above, but standard 3 bed semi rather than dormer style. Heater went from 20.5C at 11pm last night, to its set back of 16C for the night. The boiler never fired all night, but the temperature was still 18.5C when we got up at 9am and turned the stat back to 20.5C - which it had satisfied by 9:30am. Outdoors was sub- zero much of the night.
Two of the bedrooms are dorma style buy they are warm its the ground floor I have an issue with.re cavity wall insulation its something I've been looking into but seen bad reviews about damp after having it installed.