If you mean a PP setting?? of 4.0M then this shouldn't cause problems, or was/is it set to CP 4.0M, see below.
The pump (as you probably know) apart from C1,C2&C3 modes, will flash the set head pressure for a few seconds and then display the power, W,
I have mine set to PP (proportional pressure) at 4.6M which gives a actual head of ~ 3.6M with all the (10 rad) TRVs open and ~ 2.7M when they throttle down, the second photo shows a CP (constant pressure) setting of 4.0M., For info, C1=constant curve 2M, C2=constant curve ~ 3.8M & C3=constant curve 6M.
You could try a CP setting starting at say 2.5M, if no air problems then but if rads a bit slow to heat up, you can gradually increase the SP incrementally in 0.1M steps to get the optimum setting.
I have a 50 year old open vented system with some rads over 40 years old, never gave/gives any sort of air ingress problems because of the way it was installed over 50 years ago with a true combined vent& cold feed, I have seen VCP systems converted to my type which cured the problem despite havin a perfectly clean VCP system