If the two loads are different, then they will share the 12V unequally (e.g. one might get 8V and the other 4V).
Do you mean if one load has more amps then the other?
Ref the above.
No.
If you have two resistances in series then put a voltage across them they will draw current according to the total resistance of those resistors combined.
If those resistances have quite similar values then they will quite similar voltages across each one (approx equal to half the total voltage applied across them).
If, however, their resistances are more unequal then the voltages across each one will be more unequal too but the current drawn by them will be the same as each other.
So engineering tolerances and other variables make each resistance not quite the same but when doing calculations we might ignore those differences if we consider them to be quite small depending upon how we want to use them. If the differences are relatively not quite small we might want to re-evaluate the voltage differences produced.
It just depends on how much difference we might expect it to make to our finished result and what effect it might have.
If two resistances are connected across the voltage in parallel then the opposite happens - each resistance will have the same voltage across them but each will draw slightly different currents thru them in accordance with their resistance differences. Again we evaluate if that diffence needs to concern us.
Example - if we pick resistors from a batch of say 1% tolerance resistors then for our particular use we might consider the differences acceptable and of no concern.
On the other hand, if we pick resistances from a batch of 5 or 10 or 20 percent tolerance resistors we might want to make some adjustments, but there again it might still be acceptable for the particular arrangement we have in mind.
We might also be be in that acceptance if all the resistors are from the same batch therefore more likely to actually match up than if they are from different batches/from different manufacture's/in different ambient temperatures etc etc.
Again it all depends on what you are attempting to achieve and how much difference in the finished result might concern us.