I must disregard the posts about third party access and Gateway boxes as they definitely don't apply and it's somewhat lost on me anyway.
As said, the replies HAVE been digested.
And I appreciate and understand the negative thoughts on Combis ... I've spent much of my adult life with a firm dislike of them, going back to the 1980's when I sold Saunier Duval combis for a firm of direct sales cowboys.
I'll think further about the project and may well lean towards the, frequently recommended, option of unvented cylinder and either a system boiler or heat only with separate pump and expansion vessel.
But in a house with just the two of us and a rare need for two hot water draw off points at once, a Combi must at least, warrant some consideration given that the most used hot water runs are short and there's good gas and water flow and pressure provided by dedicated supplies installed specifically for the boiler - and in addition, the warranty for a new Combi covers the whole system for 7 or 8 or 10 years whereas with the unvented option the boiler's covered but that leaves the cylinder and it's controls. And it needs an annual service on top of the boiler.
BUT, the advantage of a cylinder full of hot water in the event of a temporary loss of gas or boiler breakdown is a good point and the absence of any possible concern over two hot water taps being used at the same time is another. And we know that the Combi is, statistically, probably more likely to go wrong more often -(albeit we would hope the warranty covers much of the liability ... but, equally, we keep hearing that manufacturers are prone to dismiss warranty claims given half a chance).
So, although martin43 may say (and I very much appreciate his comments) 'Your trying to worry the problem to a conclusion' I personally reckon it's not necessarily a straight forward decision and surely forums like this are here to talk about things just such as this?